NuCLEANase^®

Versatile and efficient – high-performance endonuclease for industrial applications

NuCLEANase^® is a highly active recombinantly produced endonuclease from Serratia marcescens that non-selectively degrades all forms of DNA and RNA (single-stranded, double-stranded, linear, and circular) into small 2–5 bp nucleotides.

Nucleases are already widely used in the biopharmaceutical industry and are needed in many other non-pharmaceutical processes. Yet never before has a versatile and potent nuclease been offered on the market – widely applicable, super-efficient and available in the right quality grade.

As a leading provider of innovative enzyme technologies, c-LEcta has developed a superior nuclease solution for the industry: NuCLEANase^® is perfectly suited to enable any process where the presence and amount of DNA and RNA matters.

After submitting a GRAS notification for NuCLEANase^® (GRN No.1146) to the US FDA, c-LEcta has received a positive evaluation  with no questions from the authority, which is publicly available within the GRAS Inventory List. The GRAS Notification designates that the usage of NuCLEANase^® in food applications is considered safe  under the conditions of its intended use.  

For which application field do you need NuCLEANase^®?

In food fermentation products, NuCLEANase^® ensures efficient removal of residual host DNA for regulatory compliance and viscosity reduction.

NuCLEANase^® lowers viscosity and hence facilitates the purification of phages used as natural preservatives or anti-infectives. NUCLEANase

NuCLEANase^®, as part of a multi-component cleaning formulation can enable efficient elimination of stubborn biofilms in domestic, industrial, or medical settings.

Order & test NuCLEANase^® now!

Whether it is in small quantities via our online shop or in large quantities – we are happy that you are considering our high-performance nuclease for industrial applications. So no matter if you already know what you need or if you want to discuss NuCLEANase^® with one of our experts – we are here to support you.