Versatile and efficient – high-performance endonuclease for industrial applications

NuCLEANase® is a highly active recombinantly produced endonuclease from Serratia marcescens that non-selectively degrades all forms of DNA and RNA (single-stranded, double-stranded, linear, and circular) into small 2–5 bp nucleotides.

Nucleases are already widely used in the biopharmaceutical industry and are needed in many other non-pharmaceutical processes. Yet never before has a versatile and potent nuclease been offered on the market – widely applicable, super-efficient and available in the right quality grade.

As a leading provider of innovative enzyme technologies, c-LEcta has developed a superior nuclease solution for the industry: NuCLEANase® is perfectly suited to enable any process where the presence and amount of DNA and RNA matters.


Food- and tech-grade quality

Incredibly efficient non-selective endonuclease

Highly active over a wide range of operating conditions

Manufacturing process free of antibiotics and animal-derived raw materials


For which application field do you need NuCLEANase®?

Fermentation products

In food fermentation products, NuCLEANase® ensures efficient removal of residual host DNA for regulatory compliance and viscosity reduction.

Phage production

NuCLEANase® lowers viscosity and hence facilitates the purification of phages used as natural preservatives or anti-infectives. NUCLEANase

Biofilm control

NuCLEANase®, as part of a multi-component cleaning formulation can enable efficient elimination of stubborn biofilms in domestic, industrial, or medical settings.

Order & test NuCLEANase® now!

Whether it is in small quantities via our online shop or in large quantities – we are happy that you are considering our high-performance nuclease for industrial applications. So no matter if you already know what you need or if you want to discuss NuCLEANase® with one of our experts – we are here to support you.

For smaller quantities

If you need NuCLEANase® in smaller quantities  for further testing and small piloting, you can ordner it directly in our online shop.

For larger quantities

Please get in contact to inquire about pricing in larger quantities. Our NuCLEANase® expert team looking forward to support you.

Get in touch with our NuCLEANase® expert team!

We are looking forward to support you with your question. It would our pleasure to discuss NuCLEANase® and how it can be used for your production processes.

Need support? Contact me!

Simon Ulm

Simon Ulm