NuCLEANase^® for biofilm control

NuCLEANase^®, as part of a multi-component cleaning formulation can enable efficient elimination of stubborn biofilms in domestic, industrial, or medical settings.

Biofilms are complex matrixes composed of many different molecules such as polysaccharides, proteins, lipids, and nucleic acids (DNA and RNA). DNA in form of external DNA (eDNA) has an important role in the early formation of the biofilm as a glue-like component for initial bacterial attachment to surfaces and in the subsequent early phase of biofilm development.

Microbial biofilms are known to be problematic and difficult to eliminate in industrial settings (e.g., in the food industry) or causing malodor on textiles. They are also a threat to human health, as they significantly contribute to the spread of antibiotic-resistant infections (e.g., via medical devices).

For effective combat of biofilms and to avoid disease by preventing microbial spread, whether on surfaces, textiles, or in humans, DNA/RNA needs to be address.

Wherever biofilms are of concern, NuCLEANase^® might be the solution. We provide our customers with a highly active endonuclease that can rapidly and cost-effectively degrade all forms of nucleic acid. Furthermore, c-LEcta is one of the few companies capable of engineering nucleases e.g., in terms of stability or activity.

To further advance this technology, c-LEcta is open to exclusive collaboration with industry partners to jointly address unmet industry and/or consumer needs.

Benefits