NuCLEANase® for yeast processing and flavoring

In yeast processing, NuCLEANase® is used to reduce the content of nucleic acids from yeast products or to support the degradation of RNA for the production of flavoring nucleotides and feed additives.

Yeast has been used in the food industry for centuries. Traditionally, it has been used to support the baking, brewing, or winemaking process. In recent years, more and more applications and new products have been developed from yeast, some of which have already become a must in the food industry (e.g. yeast extracts). The growing awareness of consumers about nutrition and the origin of their food makes the benefits of using natural ingredients from yeast even more prominent. Yeasts are mainly composed of proteins, carbohydrates, minerals, lipids, and nucleic acids (mainly RNA).

Although yeast is rich in healthy components, the presence of nucleic acids can become a problem if attention is not paid to overall daily consumption. Increased intake of purines, which are further broken down to uric acid, and their accumulation in the human body have been linked to human diseases such as gout and kidney stones. Therefore, lowering the nucleic acid content in some yeast products consumed in larger quantities is important for safety and health.

Yeast extracts are used in very small amounts to flavor foods to render an umami flavor or other savory tastes in soups, snacks, etc. The flavor and aroma are enhanced with the degradation and release of nucleotides from RNA, in addition to the amino acid profile. The nucleotides thus obtained can also be isolated and purified from the yeast extract and used separately as taste enhancers.

In addition, yeasts can also be used as a source of animal feed. Nucleotides are considered as a beneficial additive in feed for improved animal growth, intestinal health, and immunity. With NuCLEANase®, the nucleic acid contained abundantly in yeast can be degraded to mono- and oligonucleotides, providing all the beneficial effects of nucleotides for animal health.

No matter whether yeast extracts are to be used for flavoring, as nutritional additives, or as a feed source – whatever the purpose of yeast processing is, NuCLEANase® is a highly active endonuclease that can support the production of all these products.


  • Removes nucleic acids from yeast products
  • Supports the production of flavoring nucleotides
  • Supports the release of nucleotides for animal feed
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    Simon Ulm
    Simon UlmNuCLEANase Sales+49 341 355 214 377

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